Computational approaches for modeling human intestinal absorption and permeability
نویسندگان
چکیده
منابع مشابه
Computational approaches for modeling human intestinal absorption and permeability
Human intestinal absorption (HIA) is an important roadblock in the formulation of new drug substances. Computational models are needed for the rapid estimation of this property. The measurements are determined via in vivo experiments or in vitro permeability studies. We present several computational models that are able to predict the absorption of drugs by the human intestine and the permeabil...
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ژورنال
عنوان ژورنال: Journal of Molecular Modeling
سال: 2006
ISSN: 1610-2940,0948-5023
DOI: 10.1007/s00894-005-0065-z